Unknown bacterial strain inhibits growth of resistant pathogens
Researchers have now discovered a previously unknown bacterial strain in soil from Ireland, which is active against four of the six most important super-pathogens that are already resistant to antibiotics.
In their investigation, the scientists at Swansea University Medical School found that special soil from Ireland contains a bacterial strain that could be used in the future to combat antibiotic-resistant pathogens. The doctors published the results of their study in the English-language journal "Frontiers in Microbiology".
WHO warns of resistant super-pathogens
According to the latest studies, antibiotics-resistant super-pathogens could cost the lives of around 1.3 million people in Europe by 2050. The World Health Organization (WHO) describes the problem as one of the greatest threats to global health, food security and development today.
Where did the soil samples examined come from?
The soil, which the experts analyzed, came from an area in Fermanagh in Northern Ireland, which is also known as the Boho Highlands. It is an area of alkaline grassland and the soil is said to have healing properties. The search for replacement antibiotics to combat multi-resistance led the researchers to constantly investigate new sources.
Growth of gram-positive and gram-negative bacteria was inhibited
Traditionally, a small amount of soil was previously wrapped in a cotton cloth in the Boho Highlands and used to treat numerous diseases such as toothache, throat and throat infections. The doctors examined the healing effects of the soil samples taken from this area. They found that the growth of four of the six most important multi-resistant pathogens was inhibited by the bacteria in the earth. Scientists call the new bacterial strain Streptomyces sp. Myrophorea called. Both gram-positive and gram-negative bacteria, which differ in the structure of their cell wall, were inhibited by the earth. As a rule, so-called gram-negative bacteria are more resistant to antibiotics, the scientists say. It is not yet clear which part of the new strain prevents the pathogens from growing, but the research team is already investigating this.
Other traditional remedies should be examined more closely
This new bacterial strain is effective against four of the six most common antibiotic-resistant pathogens, including MRSA. This discovery is an important step in the fight against antibiotic resistance, explains study author Professor Paul Dyson from Swansea University. The results show that folklore and traditional medicines should be considered when looking for new antibiotics. Scientists, historians and archaeologists can all do their part in this task. It seems that part of the answer to this very modern problem could be the wisdom of the past, the expert adds.
More research is needed
The discovery of antimicrobial substances from Streptomyces sp. Hopefully myrophorea will help in the search for new drugs to treat multi-resistant bacteria that are the cause of many dangerous and fatal infections. Doctors now want to focus on cleaning and identifying these antibiotics. Additional antibacterial organisms have already been discovered in the soil, which could cover a broader spectrum of multi-resistant pathogens. (as)