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Better prevention and early detection: More risk genes for breast cancer discovered

Better prevention and early detection: More risk genes for breast cancer discovered


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Researchers discover new risk genes for ovarian and breast cancer

According to health experts, significantly more women develop breast cancer than ovarian cancer, but the mortality rate for the latter type of cancer is significantly higher. Early detection is of particular importance for both types of cancer. This could now be improved. Because researchers have discovered new risk genes for breast and ovarian cancer.

Every year, 70,000 women develop breast cancer

Breast cancer is the cancer with the highest death rate among women in Germany. Nationwide, around 17,000 die of it every year and around 70,000 fall ill each year. Health experts say that ovarian cancer is even more dangerous than breast cancer because the death rate is much higher with the former type of cancer. Prevention and early detection are of particular importance for both types of cancer. Great progress is now being made here. An international team of researchers has discovered new genetic risk factors for hereditary breast and ovarian cancer.

Breakthrough in cancer research

The German Cancer Research Center (DKFZ) recently reported that researchers have discovered 14 new breast cancer risk genes.

Cologne scientists have now made another breakthrough in cancer research.

Together with an international team of researchers, they discovered new genetic risk factors for hereditary breast and ovarian cancer.

As stated in a communication from the Cologne University Hospital, these can now be used to offer healthy women tailored prevention and early detection that is tailored to their personal risk.

Detect diseases early

According to the information, about 30 percent of all family breast cancer diseases are due to changes in certain inheritable genes.

20 years after the discovery of the previously known risk genes BRCA1 and BRCA2, the researchers have now discovered new risk genes.

In addition, 313 other genetic factors that influence the likelihood of illness were identified.

The transfer of knowledge to medical care has already begun. The BRIP1, which has been identified as a high-risk gene for hereditary ovarian cancer, has already been incorporated into routine diagnostics as a core gene.

"The findings of the Cologne researchers are taking cancer medicine a big step forward," said the Minister for Culture and Science of the State of North Rhine-Westphalia, Isabel Pfeiffer-Poensgen.

"They provide an improved risk forecast for all women and help to recognize illnesses early on through individual prevention - or even prevent them."

And Prof. Dr. Rita Schmutzler, director of the Center for Breast and Ovarian Cancer at the University Hospital Cologne, said: "Knowing the hereditary causes of breast cancer makes it possible to specifically identify preventive drugs to prevent the onset of the disease." (Ad)

Author and source information



Video: BRCA Genes and Breast Cancer (May 2022).